My Review of Alpha Brain – Does it work?

Like fireworks to wake up your brain to unlimited possibilities



Effectiveness 94%
Scientific Backing 95%
Lasting Effect 89%


  • Stack of scientifically proven ingredients
  • Safe and well documented
  • Gives you a nice calm meditative focus


  • No particular drawbacks

You may have heard about Alpha Brain. But is it really as good as advertised? Does it have any scientific backing, and … well, most importantly: does it really work?

Onnit’s flagship Earth grown nutrient based supplement, Alpha BRAIN, demonstrates statistically significant cognitive improvement for healthy, intelligent adults in a double blind, placebo controlled, randomized trial conducted by The Boston Center for Memory.

Before you decide to buy, make sure you read our review below!

For me, maximizing my brain levels and being able to stay focused and getting things done is one of the things I'd like to improve. I want to feel mentally lucid, and be able to work out, read, work on my business and improve my life.

OK, but what is it exactly?

Alpha Brain is the most well-known and popular nootropic in the United States. It is a supplement designed to help boost memory, sleep, creativity, focus, and processing speed.

I am no stranger to the 3 O’clock slump or just feeling a bit slower than I want to be some days. I hate that feeling of knowing I have a ton of things to do, but just not enough hours in the day to do them.

If Alpha Brain could do any of what it claimed, I welcome the help to power through the day and function more efficiently. 

It's the missing piece to your puzzle. 

Puzzle missing a piece

Having sold over 40 million capsules, it is clear that Alpha Brain is popular, but I wanted to check if it really worked.

Alpha Brain is an Earth Grown nutrient based supplement from Onnit. It is considered the number one nootropic in the United States.

It is aimed to make you more focused, increase energy, and more benefits that will be discussed later, as they can differ depending on how you use the supplement.

Alpha Brain works by delivering a balanced combination of nutrients to your brain, to allow for peak performance. Its design “stacks” different supplements together, in the right way, to deliver a full range of benefits to your brain.

“I believe that a time is coming where taking nootropics like Alpha BRAIN will be a standard human adaptation to get things done. Like drinking coffee. Except in a lot of ways, I like Alpha BRAIN better than coffee. It has no stimulants and works by directly stimulating neurotransmitters. So it won’t wear out your adrenals. Laying down on the pillow after a long day of crushing it is one of the most satisfying feelings in life.”

What are nootropics?

For those who are not familiar, a nootropic is a dietary supplement that helps support certain brain functions, such a memory, mental speed, and focus. Nootropics are designed to make you, and your brain, function as best it can.

I think of them like fireworks to wake up all the parts of your brain. 

Nootropics are often referred to as:

  • Smart Drugs
  • Memory Enhancers
  • Neuro-enhancers
  • Cognitive Enhancers
Fireworks in the sky

There are many of these supplements on the market. They come in different variations, and they all include different nutrients, minerals, and vitamins in what they claim to be an optimum ratio.

What makes Alpha brain different?

Alpha Brain works. And it works well. That is what makes it different from other supplements and why it is the number one nootropics in the United States.

The main thing that separated Alpa Brain from other supplements is that it is designed to be fully-balanced. Using natural ingredients and state of the art science to give you the most comprehensive benefits from any nootropic available on the market today.

The stacked design of Alpha Brain is the key for combining all the right activating ingredients into a single pill, which can be taken as desired.

Research suggest that Alpha Brain works the first time, and every time you take it.

This is one of the reasons why it is popular with beginning to intermediate cognitive supplements users. People who are just testing out the concept, see positive results and continue to take Alpha Brain.

What are the Benefits?

Since Alpha Brain is made of many ingredients, they can work independently, and with each other for a wide range of benefits. When you take it, you will notice a difference in:

Focus and Cognitive Ability:

This is the main goal for any nootropics. By increasing the oxygen and nutrients that your brain needs in the right combination with other stimulants, your brain will be able to function without distraction.

Improved Memory and Learning:

Containing ingredients that improve the plasticity of your brain and neural networks, Alpha Brain will allow your brain to send, receive, and process information faster.

Better Sleep:

Ingredients to reduce stress and anxiety not only help you focus, but also lets your body relax faster and more completely for a better nights rest.

Lucid Dreaming:

BY promoting a connection between your conscious and your subconscious, your mind can continue to influence your body as you sleep. You can process, sort, and filter information, that you might not be aware of on a conscious level.

If you are seeking a high quality, natural, balanced way to improve your focus, memory, energy, and mood, Alpha Brain could be an answer.

How does Alpha Brain work?

It is always good to know how something works before you take it. Alpha Brain works by stacking its unique combination of ingredients to activate vital areas of neurotransmitters in your brain to deliver the right nutrients to the right places.

All the ingredients work together to enhance their own positive benefits as well as the others. For example, by being more relaxed, you can fall asleep quicker, leading to more lucid dreaming, and feeling more rested when you wake up.

Alpha Brain has ingredients that stop the breakdown of Acetylcholine in your brain, which improves your ability to learn, remember, and understand new information.

In the breakdown of ingredients below, there is a more detail of how each of the 11 components that make up Alpha Brain work to help increase cognitive functioning.

Are the ingredients safe?

Since Alpha Brain uses natural Earth Grown ingredients, and a balanced design, the chances of side effects are low. Alpha Brain is regarded to have low toxicity and is free of additives that are present in other supplements known to produce negative side effects.

It is always advisable to not go over the recommended dosages. If you have any previous health conditions or take other medication, you should consider talking to a medical professional before taking any new supplements.

Recommended dosage and use

Depending on what you are looking to get out of taking Alpha Brain, there are different ways to use this supplement.

To support enhanced mental performance, it is recommended to take 2 capsules in the morning, or early afternoon, with a light meal.

To optimize your dream state, you should take 2 capsules about 4-6 hours before you go to bed.

What is in Alpha Brain?

Onnit, the manufacture of Alpha Brain, has no problem sharing what is in their supplement. This both helps us understand what we can expect from the supplement and is reassuring that they’re not hiding their ingredients like so many other companies.

Thumbs up

The ingredients in the stack

Alpha brain contains the following natural ingredients :

Alpha GPC

Alpha GPC is a raw source of acetylcholine and a neurotransmitter released by the nerves in your body. An ingredient for sharpness and mental speed, and essential for the communication between your muscles and nerves.

Huperzine A is an acetylcholinesterase (an enzyme that causes rapid hydrolysis of acetylcholine) inhibitor extracted from club moss. This makes sure that excitation of the nerves stop after transmission of an impulse.

For some years, huperzine A has been investigated as a possible treatment for diseases characterized by neurodegeneration – particularly Alzheimer's disease. A 2013 meta-analysis found that huperzine A may be efficient in improvement of cognitive function, global clinical status, and activities of daily living for individuals with Alzheimer’s disease.


This ingredient is a derivate of vinca alkaloid vincamine – a plant extract. This aids to bring oxygen and nutrients to your brain via vasodilation.


An extremely powerful DNA repairing antioxidant extracted from the inner bark of Uncaria tomentosa, a plant native to the Amazon rain forest.


One of the essential lipid compound in brain cell membranes.

Bacopa Monniera

Used for centuries in India, it is an antioxidant known to improve memory and cognition by reducing anxiety.


A brain enhancing nutrient commonly used in traditional medicine.


An amino acid important for the production of dopamine.


An amino acid which has a lot in common with GABA (Gamma-Aminobutyric Acid) – the primary inhibitory neurotransmitter. A aid to get quality sleep and rest. Will make you feel more energized and awake.

Oat Straw

A anti stress nutrient.

Vitamin B6

A catalyst to get the most out of the nutrients.

If you are not familiar with all of these ingredients, don’t worry. The takeaway is that they are safe, tested, and combined in a way to deliver the right amount of nutrients to the right parts of the brain. They all have their individual benefits and when combined correctly together, is what makes Alpha Brain work so well.

Possible side effects

Success - go get it

The ingredients used in Alpha Brain have all been deemed safe by the FDA and is considered much safer than many of its competitors.

As noted in the discussion about dosage, it is always advisable to take precaution for anything you ingest, especially if you have preexisting conditions. A few reported cases of side effects from taking Alpha Brain consisted of headaches and uncomfortable lucid dreams.

One component in Alpha Brain is Vinpocetine, which increases blood flow to the brain, but should be cautioned for people with low blood pressure.

Other ingredients, fillers, and compounds in Alpha Brain have been extensively studied and tested for safety.

Scientific Backup

Before taking Alpha Brain, I also wanted to do a quick search to see what scientific test had been done and what kind of results they came back with.

In double-blind studies, conducted by certified clinical testing organizations, a series of test were designed to see how Alpha Brain compared to a placebo supplement. Studies were carried out with randomized samples of controlled groups, with a significant sample in double-blind studies.

The results were impressive. Those who took the recommended dosage of Alpha Brain showed:

  • Improved verbal memory and executive function
  • 21% faster completion time in executive function test compared to the control group
  • 12% greater improvement in verbal recall over placebo group
  • Increased EEG readings of peak Alpha frequency, known to reflect a state of focus.

Like all good studies, the tests were repeated to verify data and make sure the results were consistent.

You can also read the entire clinical study and see the results here.

“We are an independent research organization that has conducted over one hundred clinical trials in compounds for cognitive benefit and our goal was to apply the same rigorous scientific standards and methods in the study of Alpha BRAIN as we do in any other clinical trial. Our plan from the outset was to disseminate the data from the study, regardless of whether the study demonstrated any significant findings.”
Todd Solomon, phd
Todd Solomon
Doctor, Phd.
“This is the holy grail of clinical research for a natural supplement. To be able to show statistically significant improvement in healthy adults with a natural supplement is one of the most challenging things to do. We put the reputation of our company on the line with this trial because we believe not only in the quality of product we provide, but the importance of unbiased empirical data”
Aubrey Marcus photo
Aubrey Marcus
CEO & founder of Onnit

My personal results

Knowing about the studies above and the positive reviews from other users, I was curious to see if Alpha Brain would work for me.

The results of the clinical studies confirm a lot of what I’ve experienced myself over the last month in a positive way.

I work for myself, as a self-employed software consultant. I have found in the past; sometimes my mind drifts off, and I lose focus on a task. 

With Alpha Brain, I am to focus better, work more efficiently, and have more energy to get things done. It's like tapping into an extra compartment in your brain that makes things easier.

I manage to use my time more productively and to increase my work hours without feeling tired and drained at the end of the day. This means I can enjoy my time off more.

I really feel a difference.

After using it for about a week, I felt much more awake in the mornings. Now, I get out of bed in the morning rested and with a purpose. The difference is huge. Instead of using the time to wake myself up, grab coffee, and wait for my brain to focus, I can get up and pretty much immediately start on work or whatever I have set out for myself that day.

Even after a long day at work, my mind doesn’t feel drained or exhausted. This allows me to go out and still get all the rest of stuff I have to do in life besides work done. I have the energy to go to the gym and be social with friends and family. Before, I usually just went home, tried to decompress, and would wait for work to start again the next day.

Personally, I haven’t had any negative side effects and so far only have had a positive experience. I was skeptical at first but glad I ended up trying Alpha Brain.

If anything, the only downside I can see is that it’s not the cheapest supplement out there. But you know what they say; you get what you pay for. I would rather pay for something that works, than less for something that doesn’t have the same effect.

Where to buy Alpha Brain

When you’re buying Alpha brain: make sure you buy it from the links this article has, or from Onnit’s official website.

I’m sure you can get it elsewhere, but buying from the source will ensure you quality and the best price (no middleman taking a cut).

Alpha BRAIN dietary supplement Onni

You can get a lot done by eating well, getting enough quality sleep and work out — but at some point, you will need some extra boost. I felt like I had “maxed out” my potential with regular methods and happy to have found a whole new level of productivity with Alpha Brain.

If you’ve been thinking about giving nootropics a try, but you’re not entirely sure if this is for you, the money back guarantee that onni offers makes it risk-free. The refund is simple — a quick online form, and no questions asked.

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